Endocrine Abstracts

Introduction: Thyroid dyshormonogenesis represents 15% of congenital hypothyroidism. It is a genetic disorder due to a trouble of Thyroid hormones synthesis. it implies many factors involved in this process mainly TPO Enzyme and NIS channel.Methods: We conducted a prospective study including 17 patients with Congenital Hypothyroidism belonging to 4 consanguine multigenerational Tunisian families. The thyroid dyshormonogenesis was diagnosed based on clini...

Objective: To assess the prevalence of obesity and metabolic disorders in patients with non-functional pituitary adenomas (NFPA)Patients and methods: A retrospective descriptive study of 35 patients followed for NFPA between 2000 and 2022. Metabolic syndrome was established according to the National Cholesterol Education Program Adult Treatment Panel III criteria.Results: The mean age was 52.1±11.4 years, with a male predomina...

Background and Aim: Non-functioning pituitary adenoma (NFPA) is the second most common subtype of pituitary adenomas. This study aims to detail the clinical and biological particularities of NFPA in the Tunisian population.Patients and Methods: A retrospective descriptive study of 35 patients followed for NFPA was conducted between 2000 and 2022 at the endocrinology Department of Hedi Chaker University Hospital, Sfax, Tunisia.Resul...

Objective: To determine the prevalence and the associated factors of pituitary apoplexy (PA) in non-functional pituitary adenomas (NFPA). Patients and Methods: A retrospective analytical study of 35 patients followed for NFPA between 2000 and 2022 was conducted at our institution. A pituitary magnetic resonance imaging (MRI) scan was performed in all patients.Results: The mean age was 52.1±11.4 years, with a male predominance (6...

Objective: To assess the management and therapeutic outcomes of non-functioning pituitary adenomas (NFPA) in the Tunisian population.Patients and Methods: We conducted a retrospective descriptive study of 35 patients followed for NFPA between 2000 and 2022 at the endocrinology department of Hedi Chaker University Hospital.Results: The mean age was 52.1±11.4 years, with a male predominance (61.3%). The majority of tumors were bet...

Background and aim: Acromegaly is mostly due to a somatotropic adenoma. Regarding its insidious nature, this adenoma is often revealed at an invasive stage when one or more hormonal insufficiencies are already installed. This study aims to describe the clinical and biological features of hypopituitarism associated with somatotropic adenomas.Patients and Methods : We conducted a retrospective study at the Endocrinology department of Hedi Chaker University...

Introduction: Pituitary adenomas are the most frequent sellar tumors in adults. Depending on their hormonal profile in vivo and on immunohistochemistry, they present different clinical profiles and progression outcomes. Thus, we report a case of an FSH-secreting pituitary adenoma.Observation: The patient SG is 63 years old. He complained of intermittent headaches associated with a progressive decrease in visual acuity. Ophthalmological examinati...

Introduction: Turner syndrome (TS) is a genetic condition, that results from the complete or partial loss of the second X chromosome in phenotypic females. Typically, patients with TS have growth retardation, altered pubertal development and facial dysmorphism. It’s also associated with other comorbidities.Aim: Here we report a rather rare finding which is the association of TS and Rokitansky-Küster Hauser (RKH) and we discuss the possible ethi...

IntroductionCardiothyreosis is the most dreadful complication of hyperthyroidism. In Tunisia, cardiothyreosis has rarely been analyzed. The aim of our study was to describe the clinical aspects of this disease in an adult population of southern Tunisia.MethodsRetrospective study (January 1999 to December 2018) including all cases of hyperthyroidism with cardiothyreosis followed in our department.<p class=...

BackgroundAmiodarone is a widely-used anti arrhythmic medication. Amiodarone-induced hyperthyroidism (AIH) develops in 3% of amiodarone-treated patients. AIH is classified as type 1 or type 2. Type1 AIH occurs in patients with underlying thyroid condition while Type2 AIH is a result of amiodarone causing a subacute thyroiditis. Appropriate therapy for amiodarone-induced hyperthyroidism requires a careful diagnosis that may be difficult to achieve.<p ...